Botanical warriors to combat pro-inflammation mediators – A way forward for Psoriasis management

Abstract

Abstract
Psoriasis is an auto immune condition with clinical symptoms such as scaling and inflammation and often the inflammatory mediators play a major role in psoriasis condition. Management of pro-inflammatory mediators does not require steroidal preparations instead certain botanicals can be effectively used. A tectonic shift in the treatment strategy of psoriasis is required from direct drug intervention to management of pro-inflammatory mediators. We, in the present study have established the role of certain herbs in neutralizing the pro-inflammatory molecules such as IL alpha 1, TNF and IL8 using HaCaT cell line. Our findings prove the usefulness of certain botanicals to prolong the remission phase of Psoriasis. Details are presented in the article.