MODERATING IMPACTS OF ANTIOXIDANT PROPERTIES OF GINSENG ON STANNOUS CHLORIDE INDUCED HEMATOLOGICAL PARAMETER IN RABBITS

Abstract

Panax ginseng has been used for centuries in the Orient for medicinal purposes since the 18th century. For more than 2000-year ginseng has been used in Asian countries, including Chine, Korea and Japan. stannous chloride, SnCl₂, is widely used in daily human life to con-serve soft drinks, in food manufacturing, processing and packaging, and in biocidal preparations. Five rabbits per group were assigned to 1 of 4 treatment groups:0 mg ginseng and 0 mg SnCl₂/kg BW (control); 100 mg Gs/kg BW; 20 mg SnCl₂/kg BW; 100mg Gs/kg Bw plus 20 mg SnCl₂. Results indicated that treatment with ginseng alone caused significant (P<0.05) decrease in BW and relative weight of liver, kidney, spleen, testes, and heart compared to control animals. On the other hand, the BW and relative weight of liver, kidney, lung, spleen, testes, and heart were significantly (P<0.05) increased in rabbits treated with ginseng alone as compared to control animals. treatment with ginseng caused significant increase in WBCs and significant increase in Hb, RBCs, PCV and platelets compared to control. On the other hand, stannous chloride (SnCl₂) caused significant increase in white blood cells (WBCs) and insignificant decrease in haemoglobin (Hb), red blood cells (RBCs), packed cell volume (PCV) and platelets.