Study of Platelets Behavior in COVID-19 Adult Patients

Abstract

Background:

Coronavirus disease (COVID-19) was first detected in in China and has rapidly spread and declared as a pandemic by the World Health Organization (WHO) in 2020.Thrombocytopenia was common complication, and thrombocytopenia one of risk factors association with high mortality rate.

Objective:

To investigate the relationship of thrombocytopenia with mortality in adult COVID 19 patients.

Methodology:

Retrospective observational cross section with sample size study were 90patients confirm diagnosis of COVID 19 by PCR, and admitted to hospital, we excluded age under 18 years old, Outpatient with COVID 19, Patient with preexisted hematological, Liver, renal & tumor disease, patient on aspirin. We collected first platelet count result in complete blood count (CBC) at admission patient in the hospital, we administrated questionnaire to obtain patients information as age, sex, chronic illness, time & place of admission with outcome of patient and laboratory investigation.

Results:

Thrombocytopenia was found in 48 patients with strong relationship between thrombocytopenia with mortality rate was 71.8%. And mortality rate in adult COVID19 patients with normal platelets count was 28.2%.

 Conclusion:

Thrombocytopenia is observed with high incidence in COVID 19 patient which is associated with increased mortality rate among those patients.

 Key words: Thrombocytopenia, Covid -19, Mortality rate