Variability of Uterine Leiomyoma Incidence Among Premenopausal, Perimenopausal, and Postmenopausal Women

Abstract

Background:

Uterine leiomyoma (UL) or fibroid are the most common gynecological benign tumors. Uterine fibroids are a major cause of morbidity in women of reproductive age with a high prevalence among premenopausal women. Many factors have been suggested to be causing the development and incidence of these common tumors.

Aim: To investigate the prevalence of uterine leiomyoma in different age groups.

Materials and Methods: This is a retrospective study of one hundred patients who underwent hysterectomy for uterine leiomyoma in different age groups. The data was collected from laboratory files at the Alamal Fertility Centre and additional data was collected from the Pathology Department archive, Faculty of Medicine Benghazi University. Excel has been used for data collection and descriptive analysis.

Results: Uterine leiomyoma was most common in the Premenopause 20-40   age group (72%).  The most common location of leiomyoma was intramural with 44% in premenopausal state. According to the clinical symptoms Pelvic pain and bleeding were the commonest presentations with 65% and 62%, respectively. Myomectomy was the surgical treatment of choice in the premenopausal age group (67%) to preserve women's fertility.

Conclusion: A higher prevalence of uterine fibroid in reproductive age. Uterine fibroid usually presents with Pelvic pain and bleeding. The optimal surgical option was myomectomy to preserve their fertility because all of the patients were in the premenopause age group.

Keywords: Uterine leiomyoma (UL), fibroid, premenopause, perimenopause, postmenopause, myomectomy